Intended Use:
ARA-290 is intended for research purposes only. It is widely studied in models involving neuropathy, inflammation, and tissue repair.

Storage:
Store in a cool, dry environment away from direct sunlight. After reconstitution, refrigerate at 2–8°C.

Solubility:
Reconstitute with bacteriostatic water (BAC water) for optimal performance.

Vial Size:
Standard 3ml vial (can accommodate up to 3ml BAC water).

Shelf Life:

• Lyophilized: Stable up to 24 months
• Reconstituted: Best used within 4–6 weeks

Handling:
Use sterile techniques during preparation and handling.

Neuropathic Pain Studies
Preclinical and clinical research suggests ARA-290 may significantly reduce neuropathic pain by targeting inflammation in nerve tissues without affecting normal nerve function.

Anti-Inflammatory Effects
ARA-290 has shown the ability to reduce pro-inflammatory cytokines, helping regulate excessive immune responses in various experimental models.

Tissue Repair & Regeneration
Studies indicate that ARA-290 may support tissue healing and cellular repair, especially in damaged nerve and vascular systems.

Metabolic & Microvascular Function
Emerging research shows improvements in microcirculation and metabolic signaling, making it relevant for studies involving small fiber neuropathy and vascular dysfunction.

ARA-290 works by selectively binding to the innate repair receptor (IRR), a receptor complex involved in tissue protection and healing.

Once activated, it:

• Reduces inflammation signals
• Promotes tissue repair processes
• Protects nerve cells from damage
• Improves microvascular function

Unlike traditional EPO, ARA-290 does not activate receptors responsible for red blood cell production, which allows it to focus purely on repair and anti-inflammatory pathways.